Aspergillus hubkae

Ascomycota, Pezizomycotina, Eurotiales, Aspergillaceae. Genus: ASPERGILLUS

Aspergillus hubkae Y.B. Zhou et al.
member of A. niger complex

Latest update: 29 September 2024

Colony characteristics

Colonies (CYA, 7 d, 25°C) flat, white, floccose, radially furrowed, producing hyaline exudate; margin entire. Conidial masses greenish black. Reverse cream-coloured.

Microscopy

Conidiophore stipes smooth-walled, hyaline, 500–1000 × 8–14 µm, biseriate. Vesicles spherical, 30–50 µm; metulae 20–50 × 4–7 µm; phialides flask-shaped, 7–10 × 2–4 µm; conidia (sub)spherical, 2.5–4.0 µm, brown, coarsely roughened to echinulate, with low longitudinal ridges. Sclerotia absent. Sexual state unknown.

Differential diagnostics

Aspergillus hubkae is phylogenetically very close to A. brasiliensis, but differs by a bright yellow versus cream-coloured colony reverse on CYA, and by some small morphological and physiological features.

Pathogenicity

RG-1, BSL-1. The species was isolated from a BAL of a human patient with pulmonary aspergillosis (Zhou et al., 2024), but as yet no case report has been published.

Species complex

Clinically relevant members of the A. niger series are: A. awamori, A. brasiliensisA. hubkae, A. niger and A. tubingensis.

References

Zhou et al. (2024).

Nomenclature

Aspergillus hubkae Y.B. Zhou, Houbraken & Rezaei-Matehkolaei, in Zhou, Rezaei‑Matehkolaei, Meijer, Kraak, Gerrits van den Ende, Hagen, Afzalzadeh, Kiasat, Takesh, Hoseinnejad & Houbraken – Mycopathologia 189(44): 5, 2024; type strain: CBS 150516; ITS rDNA = OR596991; BenA = OR596886; RPB2 = OR596888.

Antifungal susceptibility

AntifungalMIC90StrainsReference
AMB21Zhou et al. (2024)
5-FC41Zhou et al. (2024)
ISA21Zhou et al. (2024)
ITZ>161Zhou et al. (2024)
KTZ81Zhou et al. (2024)
PCZ0.51Zhou et al. (2024)
TBF0.51Zhou et al. (2024)
VCZ0.51Zhou et al. (2024)