Mucoromycotina, Mucorales, Saksenaeaceae. Genus: SAKSENAEA
Saksenaea erythrospora Álvarez et al.
Colony characteristics
Colonies (CzA, 37°C) growing rapidly, filling the petri dish within 4 days; aerial mycelium sparse. On MEA colonies white, floccose.
Microscopy
Hyphae branched, hyaline, 3-6 µm diam. Sporangiophores erect, generally arising singly, hyaline, soon becoming light brown, straight, unbranched, 100-150 × 7-11 µm. Sporangia terminal, multispored, flask-shaped, asperulate, 100-220 µm long, with a long (80-200 µm) neck; apex of the neck closed with a mucilaginous plug. Sporangiospores mostly ellipsoid, biconcave in a lateral view, smooth-walled, membranes collapsing at maturity, 5.0-5.5 × 2.5-3.0 µm. Zygospores not observed.
Pathogenicity
RG-1, BSL-1. A fatal case in a patient with severe burn wounds was described by Hospenthal et al. (2011), necrotizing skin infections after intramuscular injection (Chander et al., 2017) and secondary to surgery (Rodríguez et al., 2016), and an invasive sinusitis by Tendolkar et al. (2015). An infection after a sailing accident was reported by Relloso et al. (2014). Lawhon et al. (2012) described an abortion in a cow.
References
Nomenclature
Saksenaea erythrospora Álvarez, Cano, Stchigel & Guarro – J. Clin. Microbiol. 48: 4415, 2010; type strain: FMR 10672 = UTHSC 08-3606; ITS rDNA = NR_149333.1.
Antifungal susceptibility
| Antifungal | MIC90 | Strains | References |
|---|---|---|---|
| AMB | 8 | 1 | Hospenthal et al. (2011) |
| AMB | 4 | 1 | Lawhon et al. (2012) |
| AND | >16 | 1 | Hospenthal et al. (2011) |
| AND | >16 | 1 | Lawhon et al. (2012) |
| CFG | >16 | 1 | Hospenthal et al. (2011) |
| CFG | >16 | 1 | Lawhon et al. (2012) |
| ITZ | 0.5 | 1 | Hospenthal et al. (2011) |
| ITZ | 0.5 | 1 | Lawhon et al. (2012) |
| MCF | >16 | 1 | Hospenthal et al. (2011) |
| MCF | >16 | 1 | Lawhon et al. (2012) |
| PCZ | 0.5 | 1 | Hospenthal et al. (2011) |
| PCZ | 0.25 | 1 | Lawhon et al. (2012) |
| TBF | 0.03 | 1 | Hospenthal et al. (2011) |
| TBF | 0.03 | 1 | Lawhon et al. (2012) |
| VCZ | 16 | 1 | Hospenthal et al. (2011) |
| VCZ | 8 | 1 | Lawhon et al. (2012) |
Saksenaea erythrospora. a. Sporangiophore; b. sporangiospores. Scale bars A = 50 µm; B = 5 µm.
Saksenaea erythrospora, UTHSC 06-576. a. Sporangiophore; b. sporangiospores. Scale bars a = 20 µm; b = 10 µm.
